Influenza A subtype H1N1 China

Phylogeography is a field of study to identify the gene flow between locations by using the molecular sequences or amino acid sequence of species. HA (haemagglutin) segment is one of RNA in influenza A which catalyze the proteins that mediates binding of the viron to target cells and entry of the viral genome into the target cell. Nucleotide sequences of HA RNA segments sampled in China from 2009 to 2010 were used to infer the phylogenetic trees as well as phylogeography.

Each edge indicates the gene flow between locations and circles inform the relative age of the transitions for HA. As flow map describes, Beijing and Guangdong serves as epicenters for the 2009 H1N1 pandemics.

Phylogeography were inferred by using BEAST and Beagle software and visualized by SpreaD3. Neon, High performace computing provided by the University of Iowa was used for inference.